Antipsychotics May Increase Diabetes Risk In Children

Category: Diabetes     Author: Georgina Tyburski     Posted: Friday - July 24, 2015

From healio.com

Children initiating treatment with second-generation antipsychotics are at increased risk for incident type 2 diabetes, especially among those using antidepressants, according to recent study findings published in JAMA Pediatrics.

“With such vast numbers of children being exposed to these medications, the implications for potential long-lasting harm can be jarring,” David M. Rubin, MD, MSCE, of The Children’s Hospital of Philadelphia, said in a press release.

Rubin and colleagues evaluated U.S. children aged 10 to 18 years enrolled in Medicaid between 2003 and 2007 to determine whether initiation of second-generation antipsychotic treatment is associated with an increased risk for incident type 2 diabetes. Overall, 107,551 second-generation antipsychotic initiators and 1,221,434 noninitiators were evaluated.

The researchers found that compared with noninitiators, the risk for diabetes was increased among initiators (OR = 1.51; 95% CI, 1.35-1.69). There was a 38 per 10,000 children risk for developing diabetes during 20 months for initiators compared with 25 per 10,000 children for noninitiators.